1 Higher Institute of Medical Techniques of Lubumbashi, Department of Laboratory, Democratic Republic of Congo.
2 Faculty of Medicine, Department of Biomedical Sciences, University of Lubumbashi, Democratic Republic of Congo.
3 Faculty of Medicine, Department of Internal Medicine, University of Lubumbashi, Democratic Republic of Congo.
World Journal of Advanced Research and Reviews, 2026, 29(01), 1247-1256
Article DOI: 10.30574/wjarr.2026.29.1.0112
Received on 08 December 2025; revised on 14 January 2026; accepted on 17 January 2026
Introduction: Antibiotics play a crucial role in reducing morbidity and mortality from infectious diseases worldwide. The objective of this study was to evaluate the MIC of beta-lactams and fluoroquinolones marketed in pharmacies in the city of Lubumbashi.
Material and methods: This is a descriptive cross-sectional study conducted from December 22, 2024 to March 10, 2025. The study involved community-acquired Escherichia coli strains isolated from urinary tract infections; as well as 4 antibiotics from 3 different pharmaceutical companies operating in Lubumbashi: ciprofloxacin; norfloxacin; amoxicillin + clavulanic acid and ceftriaxone.
Results: The pharmaceutical firm 1 has revealed that the Escherichia coli strains had MICs within the normal range for amoxicillin + clavulanic acid (5 strains/5); norfloxacin (3 strains/2).
For company 2, amoxicillin + clavulanic acid and norfloxacin had MICs within the normal range for all 5 strains. And for company 3, all 5 strains had MICs within the normal range for amoxicillin + clavulanic acid. The MBC/MIC report of antibiotics from different pharmaceutical firms, for which the MICs were within CLSI standards, revealed that the CMIs were bactericidal.
Conclusion: The antibiotics from pharmaceutical company 2 performed well compared to those from other companies; followed by the antibiotics from pharmaceutical company 1 and those from pharmaceutical company 3.
Evaluation; Quality; Antibiotics; MIC; Lubumbash
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Charles Kimuni Kamona, Nono Ndete Lusenge, Eric Kasamba Ilunga and Claude Mwamba Mulumba. Evaluation of the quality of antibiotics sold in Lubumbashi (DR Congo) by MIC and MBC. World Journal of Advanced Research and Reviews, 2026, 29(01), 1247-1256. Article DOI: https://doi.org/10.30574/wjarr.2026.29.1.0112.
Copyright © 2026 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0