1 Bachelor Program in Dentistry, Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.
2 Department of Oral Biology, Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.
3 Residency Program in Dental Radiology, Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.
World Journal of Advanced Research and Reviews, 2025, 28(03), 772-776
Article DOI: 10.30574/wjarr.2025.28.3.4100
Received 26 October 2025; revised on 08 December 2025; accepted on 10 December 2025
Background and aim: Inflammatory Bowel Disease (IBD) is divided into several types, with one of the most prevalent being Crohn’s disease (CD). CD is an inflammatory disease that affects almost the entire digestive tract. Several studies have indicated that patients with Crohn’s disease experience issues in the oral cavity, with one of the most common complaints being periodontitis. This study aims to analyze the increased risk of periodontitis in patients with Crohn’s disease.
Purpose: To analyze the increased risk of periodontitis in patients with Crohn’s disease and identify the underlying mechanisms that link both conditions.
Methods: This research employed a literature review method using PubMed and Google Scholar databases.
Results: Identified five relevant literature sources using the predetermined keywords. Among the five sources, four concluded that Crohn’s disease is associated with an increased risk of periodontitis. In fact, there is a two-way relationship between the two conditions due to the interaction between the environment and the immune system within the body.
Conclusion: Crohn’s disease can lead to an increased risk of periodontitis. Both conditions exhibit a two-way relationship due to environmental interactions and the body's immune response to the inflammatory process.
Inflammatory Bowel Disease; Crohn’s Disease; Periodontitis; Oral Cavity; Inflammatory Disease
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Daisy Salma Erlita Susanto, Zeva Daazra Malaika, Tantiana and Christian Victor Budikusuma. Increased Risk of Periodontitis in Patients with Crohn’s Disease. World Journal of Advanced Research and Reviews, 2025, 28(03), 772-776. Article DOI: https://doi.org/10.30574/wjarr.2025.28.3.4100.
Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0