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eISSN: 2581-9615 || CODEN (USA): WJARAI || Impact Factor: 8.2 || ISSN Approved Journal

Comparative Study of Antimicrobial Action of Aloe vera and Garlic Against Candidal Albicans in Clinical Isolates

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Ramoni Tiamiyu Adebisi 1, Oludele Mathew Akinleye 2, *, Adekunle Akinola Fowotade 3, Falitat Funke Ogundare 4 and Olufemi Margret Ibikunle 5

1 Department of Biological Science, Lead City University, Ibadan.

2 Department of Medical Laboratory Science, Ajayi Crowther University, Oyo.

3 Department of Pathology, University of Ilorin Teaching Hospital, Kwara State.

4 Department of Chemical Pathology, Lagos State University College of Medicine, Ikeja.

5 Department of Medical Laboratory Science Lagos State College of Medicine, Ikeja.

Research Article

World Journal of Advanced Research and Reviews, 2025, 28(03), 358-365

Article DOI: 10.30574/wjarr.2025.28.3.3261

DOI url: https://doi.org/10.30574/wjarr.2025.28.3.3261

Received on 11 August 2025; revised on 30 November 2025; accepted on 03 December 2025

Candida albicans is an opportunistic fungal pathogen that commonly causes infections in humans, particularly in immunocompromised individuals. It is responsible for various infections, including oral thrush, vaginal candidiasis, and systemic candidiasis with mortality rate of 25-60% in systemic candidemia

Herbal drugs have found wide spread use in many countries because they are easily, available, cheaper, and safer than synthetics drug (Wanjari & Wanjari, 2019). According to World Health Organization (WHO) about 80% of people worldwide are currently depending on traditional medicine for their primary health care needs.

The aim of our study was to compare the antimicrobial efficacy of garlic (Allium Sativum) and Aloe vera (Aloe barbadensis millar) extracts against Candida albicans. Zones of inhibition were measured in millimeters to determine antifungal activity.

It is concluded that garlic extract is more effective than aloe vera in inhibiting the grow of Candida alblicans.

Aloe vera; Garlic; Candida alblicans; Anti-fungal agents

https://journalwjarr.com/sites/default/files/fulltext_pdf/WJARR-2025-3261.pdf

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Ramoni Tiamiyu Adebisi, Oludele Mathew Akinleye, Adekunle Akinola Fowotade, Falitat Funke Ogundare and Olufemi Margret Ibikunle. Comparative Study of Antimicrobial Action of Aloe vera and Garlic Against Candidal Albicans in Clinical Isolates. World Journal of Advanced Research and Reviews, 2025, 28(03), 358-365. Article DOI: https://doi.org/10.30574/wjarr.2025.28.3.3261.

Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

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