Department of Pneumology, Mohammed VI University Hospital, LRMS Laboratory, Faculty of Medicine and Pharmacy of Marrakech, Cadi Ayyad University, Marrakech, Morocco.
World Journal of Advanced Research and Reviews, 2025, 28(02), 2553-2557
Article DOI: 10.30574/wjarr.2025.28.2.3994
Received on 20 October 2025; revised on 26 November 2025; accepted on 29 November 2025
Chronic hypersensitivity pneumonitis (HP) is a rare interstitial lung disease caused by environmental antigen exposure. This report describes two cases of chronic HP associated with Sjögren's syndrome. The first case involved a 55-year-old woman exposed to pigeon droppings, presenting with dyspnea and alveolitis confirmed by bronchoalveolar lavage and positive anti-pigeon antibodies. The second case was a 41-year-old woman exposed to mold, presenting with basal fibrosis and positive anti-SSA/SSB antibodies. Both cases demonstrated salivary gland lymphocytic sialadenitis consistent with Sjögren's syndrome. Treatment included antigen avoidance, corticosteroids, and azathioprine. These cases underscore the importance of thorough diagnostic evaluation and a multidisciplinary approach for optimal management of HP and associated autoimmune diseases.
Hypersensitivity pneumonitis; Sjögren's syndrome; Autoimmune diseases; Antigen exposure; Corticosteroids; Immunosuppressive therapy
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S. Moatassime, A. Mourhri, M. Ijim, O. Fikri and L. Amro. Gougerot-Sjögren Syndrome Associated with Hypersensitivity Pneumonitis: Report of Two Cases". World Journal of Advanced Research and Reviews, 2025, 28(02), 2553-2557. Article DOI: https://doi.org/10.30574/wjarr.2025.28.2.3994.
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