1 Department of Cardiac Surgery, MTI-HMC / KGMC Peshawar, Pakistan.
2 Aga Khan University, Karachi, Pakistan.
3 Department of Medicine, Khyber Medical College, Pakistan.
4 Cardiovascular medicine department, Hayatabad medical complex Peshawar Pakistan.
5 Department of Medicine, Khyber Girls Medical College, Peshawar.
World Journal of Advanced Research and Reviews, 2025, 28(02), 1053-1060
Article DOI: 10.30574/wjarr.2025.28.2.3620
Received on 03 October 2025; revised on 08 November 2025; accepted on 11 November 2025
Objectives: This study evaluates the outcomes of intra-aortic balloon pump (IABP) use in high-risk patients with impaired left ventricular (LV) function (EF ≤45%) undergoing coronary artery bypass grafting (CABG).
Methodology: A retrospective analysis of 1683 CABG patients identified 481 with significant LV dysfunction, of whom 55 (11.4%) required IABP support at Hayatabad Medical Complex (2018–2025). Data from these 55 patients were analyzed for outcomes and predictors.
Results: Mean age was 59.4 ± 10.5 years, mean EF 33.9 ± 3.7%. Most were male (81.8%), with comorbidities including hypertension (45.5%) and diabetes (29.1%). Mean CPB time was 166.1 ± 30.0 minutes; 98.2% received LIMA-LAD grafting. Most (90.9%) underwent elective CABG, while 5.5% required emergent CABG (e.g., ventricular septal rupture). Postoperative outcomes included in-hospital mortality (38.2%), re-intubation (29.1%), and arrhythmias (23.6%).
Conclusion: IABP is an effective first-line mechanical support in high-risk CABG patients with LV dysfunction, with better outcomes when inserted early intraoperatively. However, its use remains associated with increased mortality. Further prospective studies are needed to optimize its role.
Intra-aortic balloon pump (IABP); CABG; LV dysfunction; Cardiac surgery; Mortality
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Muhammad Aasim, Attaul Mohsin, Raheel Khan, Raheela Aziz, Muhammad Hasnain Mankani, Aizaz Ali, Ayesha Zahid, Muhammad Awais and FNU Sawaira. Use of Intra-aortic balloon pump in Ischemic Heart Disease Patients with Impaired Left Ventricle: 7 Years’ Experience in MTI-HMC, Peshawar, Pakistan. World Journal of Advanced Research and Reviews, 2025, 28(02), 1053-1060. Article DOI: https://doi.org/10.30574/wjarr.2025.28.2.3620.
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