Dermatofibrosarcoma Protuberans: A study of 10 cases

Dermatofibrosarcoma protuberans (DFSP) is a skin fibroblastic tumour that is locally aggressive, with a tendency for high local recurrence rate but low metastatic risk. Diagnosis is suspected clinically and confirmed by Histology. The standard treatment is complete surgical excision with wide local margins, in order to reduce the recurrence rate. Methods: Retrospective study of patients with DFSP diagnosed during 2023–2024 in University Hospital Center of Mohammed VI of Tangier. The medical records were examined to collect the following informations: age, sex, tumour location, evolution time, diameter, treatment, and follow-up. Results: 10 patients were included in this study (6 women/4 men, mean age 43.5 years). Tumors were located on the back in 6 cases, the abdomen in 2, the thorax in 1, and the face in 1 case. Surgical treatment was indicated in 9 patients (90%). recurrences were observed on 3 patients (30%). Conclusion: DFSP is a low- to intermediate-grade malignancy that commonly affects young to middle-aged individuals. The treatment of choice is surgery, however, adjuvant therapies, such as radiation and targeted therapy, should be considered for patients who are not candidates for surgical excision.