A Randomized Open- Labelled Controlled Clinical Study to Evaluate the Efficacy of Jeevantyadi Yamaka Matra Basti in the Management of Artava Kshaya with Special Reference to Oligomenorrhea

Background: Artava Kshaya (menstrual irregularities including oligomenorrhea) is increasingly prevalent due to modern lifestyle factors and has significant impact on women’s reproductive health. Conventional hormonal therapies have side effects, highlighting the need for alternative treatments. Ayurvedic intervention using Jeevantyadi Yamaka Matra Basti may offer a safer, effective option by addressing the condition's root cause.

Aim: To clinically evaluate the efficacy of Jeevantyadi Yamaka Matra Basti in the management of Artava Kshaya w.s.r. to Oligomenorrhea.

Materials and methods: A randomized open-labelled controlled clinical study with 30 patients diagnosed with Artava Kshaya was conducted. Patients were equally divided into two groups receiving Jeevantyadi Yamaka Matra Basti or Phalakalyana Ghrita Matra Basti once daily for 7 days per menstrual cycle, over 2 months. Assessments pre- and post-intervention included duration of menstrual bleeding, interval between two cycles, amount of menstrual bleeding, intensity of pain during menstrual bleeding, assessment of pain- grading by VMS. Statistical analysis used non-parametric tests.

Result: Within the Group: Group A (Jeevantyadi Yamaka) showed significant improvement in interval between two cycles (p=0.009), duration of menstrual bleeding (p=0.002), amount of menstrual bleeding (p=0.003), and intensity of pain during menstrual cycle (p=0.016). Group B showed significant improvement only in amount of menstrual bleeding (p=0.046) and intensity of pain during menstrual cycle (p=0.015).

Between the Group: Jeevantyadi Yamaka Matra Basti demonstrated superior efficacy compared to Phalakalyana Ghrita Matra Basti in regulating menstrual cycle interval and bleeding duration.

Interpretation & conclusion: Jeevantyadi Yamaka Matra Basti is an effective and safe Ayurvedic treatment for Artava Kshaya, addressing hormonal and systemic imbalances responsible for oligomenorrhea. Its dual lipid base enhances drug absorption and tissue nourishment, leading to improved menstrual parameters and symptom relief. This therapy can be considered a promising alternative to conventional hormonal treatments with fewer side effects.