1 Undergraduate Student, Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.
2 Departement of Oral Biology, Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.
World Journal of Advanced Research and Reviews, 2025, 25(01), 309-313
Article DOI: 10.30574/wjarr.2025.25.1.0005
Received on 25 November 2024; revised on 04 January 2025; accepted on 06 January 2025
Background: Hypertension patients are recorded by WHO to increase continuously along with the increase in population, accounting for 29% of the world's citizens suffering from hypertension. Most people with hypertension take hypertension drugs. The use of antihypertensive drugs varies and can cause several side effects on the oral cavity, especially the salivary flow rate. The purpose of this study was to evaluate the flow rate and composition of saliva in hypertensive patients who take hypertension drugs. This study uses a systematic review method by searching for articles related to evaluating the flow rate and composition of saliva in hypertensive patients who take antihypertensive drugs that have been published in journals. The literature search was conducted in April 2023 through google scholar and PubMed. Journals were selected based on inclusion and exclusion criteria through a critical appraisal process.
Result: The use of antihypertensive drugs, such as captopril and amlodipine, significantly decreased the salivary flow rate compared to the control group. In amlodipine users, 93.33% experienced a very low reduction in salivary flow rate, while in captopril users it was 83.33%.
Conclusion: Regular use of the antihypertensive drugs captopril and amlodipine may decrease salivary flow rate.
Hypertension; Antihypertensives; Captopril; Amlodipine; Salivary flow rate
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Athica Puteri Basyari, Selvina Alisandra Fahrial, Tantiana, drg. and M. Kes. Evaluation of salivary flow rate and composition in hypertensive patients taking antihypertensive drugs consuming. World Journal of Advanced Research and Reviews, 2025, 25(01), 309-313. Article DOI: https://doi.org/10.30574/wjarr.2025.25.1.0005.
Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0