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eISSN: 2581-9615 || CODEN (USA): WJARAI || Impact Factor: 8.2 || ISSN Approved Journal

Intrahepatic cholestasis of pregnancy: A case report

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Vanessa Rocio Villanueva Guerrero 1, *, Fabio David Rodriguez Carrascal 1, Germán Pertuz Rebolledo 1, Fredy Pacheco Miranda 1, Victor Jaimes Fuentes 1 and Ricardo David Rodriguez Camargo 1

¹ Department of Internal Medicine, Faculty of Health Sciences, Universidad Libre, Barranquilla, Colombia.

Case Report

World Journal of Advanced Research and Reviews, 2025, 25(03), 824-828

Article DOI: 10.30574/wjarr.2025.25.3.0773

DOI url: https://doi.org/10.30574/wjarr.2025.25.3.0773

Received on 27 January 2025; revised on 07 March 2025; accepted on 09 March 2025

Intrahepatic cholestasis of pregnancy is the most common liver disease that occurs exclusively during pregnancy. Its development poses a potential risk to the mother, but especially to the fetus, and requires appropriate management and follow-up. The clinical presentation is characterized by pruritus and elevation of bile acid concentration, but there may be alterations in hepatic biochemical parameters, leading to a thorough differential diagnosis to rule out other liver diseases that may occur during pregnancy.

We present the case of a pregnant woman who presented with pruritus since the end of the first trimester with the finding of elevated bile acid concentration in the moderate range and in whom other possible causes of liver involvement were ruled out.

Intrahepatic cholestasis of pregnancy; Liver diseases of pregnancy; Gestational pruritus; Bile acids; Pregnancy complications; Hepatocellular injury

https://journalwjarr.com/sites/default/files/fulltext_pdf/WJARR-2025-0773.pdf

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Vanessa Rocio Villanueva Guerrero, Fabio David Rodriguez Carrascal, Germán Pertuz Rebolledo, Fredy Pacheco Miranda, Victor Jaimes Fuentes and Ricardo David Rodriguez Camargo. Intrahepatic cholestasis of pregnancy: A case report. World Journal of Advanced Research and Reviews, 2025, 25(03), 824-828. Article DOI: https://doi.org/10.30574/wjarr.2025.25.3.0773.

Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

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