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eISSN: 2581-9615 || CODEN (USA): WJARAI || Impact Factor: 8.2 || ISSN Approved Journal

Tumor lysis syndrome: A review

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Konstantina Satolia *

Intensive Care Unit, General Hospital of Nikaia, Piraeus "Agios Panteleimon" Greece.

Review Article

World Journal of Advanced Research and Reviews, 2025, 25(03), 361-367

Article DOI: 10.30574/wjarr.2025.25.3.0718

DOI url: https://doi.org/10.30574/wjarr.2025.25.3.0718

Received on 25 January 2025; revised on 03 March 2025; accepted on 05 March 2025

Introduction: Tumor lysis syndrome is a clinical condition that can manifest suddenly or following the initiation of chemotherapy. 

Purpose: To provide an overview of tumor lysis syndrome. 

Methodology: This narrative review was conducted through a bibliographic search of reviews and research studies sourced from international databases. The exclusion criterion for the articles was any language other than English and Greek. 

Results: Tumor lysis syndrome is a metabolic and oncological emergency commonly observed in clinical practice, reflecting the consequences of rapid tumor cell breakdown. It leads to disturbances in the patient's metabolic and electrolyte levels, causing hyperkalemia, hyperphosphatemia, hypocalcemia, and hyperuricemia. If not treated promptly, these conditions can pose a life-threatening risk to patients.  

Conclusion: Tumor lysis syndrome is an emergency clinical condition linked to metabolic and electrolyte disturbances that, if not addressed quickly, can be fatal for patients. 

Tumor Lysis Syndrome; Management; Metabolic Disorders; Therapeutic management; Prognosis

https://journalwjarr.com/sites/default/files/fulltext_pdf/WJARR-2025-0718.pdf

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Konstantina Satolia. Tumor lysis syndrome: A review. World Journal of Advanced Research and Reviews, 2025, 25(03), 361-367. Article DOI: https://doi.org/10.30574/wjarr.2025.25.3.0718.

Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

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